Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.64 |
| ▸ | PDCD4 | Q53EL6 | 7/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9282678 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9279629 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9282464 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9281384 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9282461 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9278952 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9282676 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9278942 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9282667 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 | |
| SCHEMBL9279635 | 1.00 | DAGLA (0.64) | DAGLAPDCD4GPR84CNR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466708-A | Carbamyloxyoxetanone compounds | HOFFMANN-LA ROCHE INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5376674-A | Lipase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5260310-A | Oxetanone compounds and pharmaceutical compositions containing them | HOFFMANN-LA ROCHE INC. (US) | 1993-11-09 | — | — | US | disclosed |