Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | CHRND | Q07001 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100051 | 0.88 | CHRNA1 (0.49) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9100040 | 0.88 | CHRNA1 (0.49) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL31478950 | 0.88 | CHRNA1 (0.49) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9102500 | 0.87 | CHRNA1 (0.51) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9102498 | 0.87 | CHRNA1 (0.51) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9104582 | 0.85 | CHRNA1 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9104592 | 0.85 | CHRNA1 (0.46) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9102981 | 0.81 | CHRNA1 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL31478927 | 0.81 | CHRNA1 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL9102990 | 0.81 | CHRNA1 (0.47) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |