SCHEMBL9280225

SCHEMBL9280225

CN(C)C(CCN)NCCNCCN

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
CYP2C9 P11712 2/20 0.48
CA12 O43570 5/20 0.44
CA6 P23280 5/20 0.44
CA7 P43166 5/20 0.44
CA9 Q16790 5/20 0.44
CA14 Q9ULX7 5/20 0.44
CA5B Q9Y2D0 5/20 0.44
CA2 P00918 4/20 0.44
CA4 P22748 4/20 0.44
CA5A P35218 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
CA3 P07451 3/20 0.44
ALOX15 P16050 3/20 0.44
LMNA P02545 2/20 0.44
CA1 P00915 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503505 0.87 CYP2C9 (0.44) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL10506433 0.83 TDP1 (0.39) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL3914566 0.81 CA12 (0.41) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL8987402 0.81 CA12 (0.41) CYP2C19CYP2C9CA12CA6CA7
SCHEMBL9746468 0.79 CYP2C9 (0.46) CYP2C19CYP2C9TDP1ALDH1A1
SCHEMBL6248960 0.79 CYP2C9 (0.32) CYP2C19CYP2C9
SCHEMBL3026480 0.75 CYP2C9 (0.33) CYP2C19CYP2C9
SCHEMBL3377833 0.74 CYP2C9 (0.34) CYP2C19CYP2C9TDP1ALDH1A1MAPT
SCHEMBL4340553 0.74 CYP2C9 (0.30) CYP2C19CYP2C9
SCHEMBL8591941 0.73 CYP2C9 (0.32) CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2646511-A1 CURABLE COMPOSITION Construction Research & Technology GmbH (DE) 2013-10-09 EP disclosed
WO-2012072502-A1 CURABLE COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-06-07 WO disclosed