Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280800 | 1.00 | TDP1 (0.50) | TDP1PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL9966867 | 0.91 | PARP15 (0.55) | TDP1PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL11312939 | 0.84 | PARP15 (0.46) | TDP1PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL11312915 | 0.84 | PARP15 (0.46) | TDP1PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL3572304 | 0.83 | PARP15 (0.57) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL5118241 | 0.83 | PARP10 (0.57) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL8673552 | 0.82 | PARP15 (0.51) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL385757 | 0.81 | PARP10 (0.58) | TDP1PARP15PARP10PARP2 | |
| SCHEMBL29024848 | 0.80 | PARP15 (0.64) | TDP1PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL11316847 | 0.80 | PARP15 (0.43) | TDP1PARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7233113-A | — | — | None | — | — | JP | disclosed |
| JP-H07233113-A | CYCLOHEXYLMETHOXYBENZENE DERIVATIVE | ASAHI DENKA KOGYO KK | 1995-09-05 | — | — | JP | disclosed |