Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284198 | 1.00 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL12160056 | 0.98 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL12160014 | 0.98 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL2775603 | 0.98 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL12160094 | 0.98 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL18475635 | 0.98 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| SCHEMBL689813 | 0.98 | MAPK13 (0.46) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| Hydrochloric Acid SCHEMBL21531494 | 0.97 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| Hydrochloric Acid SCHEMBL22613427 | 0.97 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14SCN10A | |
| Hydrochloric Acid SCHEMBL19689541 | 0.97 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136027-A1 | Phenyl Ethynyl Derivatives As Hepatitis C Virus Inhibitors | JANSSEN SCIENCES IRELAND UC (IE) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136027-A1 | Phenyl Ethynyl Derivatives As Hepatitis C Virus Inhibitors | HAVCR2, ZC3HAV1, EIF2AK2 | MAPK13 1655/4885MAPK12 2605/4885MAPK11 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.