SCHEMBL9282984

SCHEMBL9282984

CSCCNC(O)C(O)Cc1c[nH]c2c(=O)[nH]c(N)nc12

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNP P00491 11/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1946202 0.78 PNP (0.44) PNP
SCHEMBL9281120 0.78 PNP (0.48) PNP
SCHEMBL1945739 0.75 PNP (0.69) PNP
SCHEMBL1947156 0.75 PNP (0.69) PNP
SCHEMBL1946527 0.75 PNP (0.69) PNP
SCHEMBL1945048 0.75 PNP (0.69) PNP
SCHEMBL1948382 0.75 PNP (0.69) PNP
SCHEMBL1947944 0.75 PNP (0.57) PNP
SCHEMBL9282586 0.74 PNP (0.50) PNP
SCHEMBL1946208 0.74 PNP (0.68) PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012074912-A1 METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2012-06-07 WO claimed
WO-2017062421-A1 USE OF MTAP INHIBITORS FOR THE TREATMENT OF LUNG DISEASE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2017-04-13 WO disclosed
WO-2012074912-A1 METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2012-06-07 WO disclosed