SCHEMBL9285754

SCHEMBL9285754

Cc1ccc2c(c1)c1cc(-c3cccc4c3oc3ccccc34)ccc1n2-c1cccc(-c2nc3ccccc3n2-c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.41
ALOX5 P09917 1/20 0.39
ALDH1A1 P00352 5/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 2/20 0.39
POLB P06746 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HDAC1 Q13547 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
PDE10A Q9Y233 1/20 0.37
RXFP1 Q9HBX9 2/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
RECQL P46063 1/20 0.36
PPARG P37231 1/20 0.36
NR2E3 Q9Y5X4 1/20 0.36
NCOR2 Q9Y618 1/20 0.36
TP53 P04637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290082 0.95 PTGER4 (0.41) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9288691 0.95 PTGER4 (0.45) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9288705 0.95 ESR1 (0.41) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9289619 0.95 PTGER4 (0.41) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9285722 0.95 PTGER4 (0.44) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9289628 0.94 PTGER4 (0.41) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9288680 0.94 PTGER4 (0.41) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9290143 0.93 PTGER4 (0.42) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9290156 0.92 PTGER4 (0.42) PTGER4ALOX5ALDH1A1LMNAGAA
SCHEMBL9290148 0.92 PTGER4 (0.41) PTGER4ALOX5ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL PTGER4 1970/4885ALOX5 1378/4885ALDH1A1 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.