Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846109 | 0.72 | PDK2 (0.48) | PDK2RAB9ASMN1; SMN2CYP1A2TRPM8 | |
| SCHEMBL31547671 | 0.71 | POLB (0.48) | CYP1A2RECQL | |
| SCHEMBL920891 | 0.71 | POLB (0.48) | CYP1A2RECQL | |
| SCHEMBL2647877 | 0.70 | PDK2 (0.50) | PDK2SMN1; SMN2TRPM8 | |
| SCHEMBL8553788 | 0.70 | CA1 (0.46) | TP53RAB9ASMN1; SMN2EPHX2CYP1A2 | |
| SCHEMBL17194991 | 0.68 | PDK2 (0.45) | PDK2TP53RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL30996534 | 0.67 | EPHX2 (0.37) | PDK2TP53RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL6609423 | 0.67 | TRPV1 (0.42) | TP53RAB9ASMN1; SMN2TRPM8NPC1 | |
| SCHEMBL19207092 | 0.66 | CSNK2A1 (0.44) | TP53RAB9ASMN1; SMN2GAA | |
| SCHEMBL31336940 | 0.66 | CSNK2A1 (0.44) | TP53RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995031452-A1 | THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |