Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414393 | 0.96 | — | — | |
| SCHEMBL30324 | 0.96 | — | — | |
| SCHEMBL5574727 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL1377708 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL20610088 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL1374457 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL5575885 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL20526164 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL5575653 | 0.92 | TSHR (0.61) | — | |
| SCHEMBL873434 | 0.92 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401888-A | Reaction of vinyl epoxide with aryl halide, vinyl halide or vinyl sulfonate | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1995-03-28 | — | — | US | disclosed |