Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464256 | 0.89 | EPHX1 (0.60) | EPHX1ALDH1A1CYP1A2PTAFRPPARG | |
| SCHEMBL7155865 | 0.89 | EPHX1 (0.60) | EPHX1ALDH1A1CYP1A2PTAFRPPARG | |
| SCHEMBL7155873 | 0.89 | EPHX1 (0.60) | EPHX1ALDH1A1CYP1A2PTAFRPPARG | |
| SCHEMBL11052003 | 0.87 | EPHX1 (0.64) | EPHX1ALDH1A1CYP1A2PTAFRPPARG | |
| SCHEMBL17934308 | 0.85 | SLC6A4 (0.48) | EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19396003 | 0.85 | SLC6A4 (0.48) | EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17930126 | 0.85 | SLC6A4 (0.48) | EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6479195 | 0.83 | EPHX1 (0.59) | EPHX1ALDH1A1CYP1A2PTAFRPPARG | |
| SCHEMBL11741674 | 0.82 | EPHX1 (0.50) | EPHX1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17541782 | 0.82 | SLC6A4 (0.57) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447942-A | Treatment of bronchoconstriction | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1995-09-05 | — | — | US | disclosed |