Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 4/20 | 0.52 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763070 | 0.90 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9097116 | 0.89 | TDP1 (0.76) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9097133 | 0.89 | TDP1 (0.76) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9173100 | 0.87 | TDP1 (0.78) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9101447 | 0.86 | TDP1 (0.65) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9101416 | 0.86 | TDP1 (0.65) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7765603 | 0.85 | TDP1 (0.59) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL7763045 | 0.85 | MAPT (0.62) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9097338 | 0.85 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10354146 | 0.83 | NR1I2 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408034-B1 | 3-Substituted vinyl cephalosporin derivatives | EISAI CO LTD (JP) | 1996-05-01 | — | — | EP | claimed |