Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.55 |
| ▸ | CIT | O14578 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241026 | 0.80 | TSHR (0.49) | HTTSMN1; SMN2HDAC2 | |
| SCHEMBL7252279 | 0.74 | JAK2 (0.58) | LMNAHTTSMN1; SMN2HDAC2 | |
| SCHEMBL10568742 | 0.73 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2 | |
| SCHEMBL9287001 | 0.73 | TOP1 (0.52) | AAK1CIT | |
| SCHEMBL4526397 | 0.71 | AAK1 (1.00) | AAK1CIT | |
| SCHEMBL17783166 | 0.71 | AAK1 (1.00) | AAK1CIT | |
| SCHEMBL245938 | 0.71 | MAPT (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL9582303 | 0.68 | RPS6KA3 (0.43) | CITLMNASMN1; SMN2 | |
| SCHEMBL10878244 | 0.68 | CA1 (0.50) | AAK1SMN1; SMN2SPHK1 | |
| SCHEMBL8187863 | 0.68 | NPC1 (0.40) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345171-B1 | Metalloporphyrine derivatives, their therapeutical use and their use in the preparation of hybrid molecules | CENTRE NAT RECH SCIENT (FR) | 1995-12-13 | — | — | EP | disclosed |
| EP-0345171-A1 | Metalloporphyrine derivatives, their therapeutical use and their use in the preparation of hybrid molecules | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1989-12-06 | — | — | EP | disclosed |