Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258027 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL637920 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9288114 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL637921 | 1.00 | HMGCR (0.82) | HMGCR | |
| SCHEMBL9726556 | 1.00 | HMGCR (0.82) | HMGCR | |
| Water SCHEMBL9726735 | 0.99 | HMGCR (0.81) | HMGCR | |
| Water SCHEMBL10425262 | 0.99 | HMGCR (0.81) | HMGCR | |
| SCHEMBL10426406 | 0.97 | HMGCR (0.78) | HMGCR | |
| SCHEMBL10426316 | 0.97 | HMGCR (0.78) | HMGCR | |
| SCHEMBL9726682 | 0.94 | HMGCR (0.74) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658550-A2 | Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |