Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10261186 | 1.00 | ESR1 (0.33) | ESR1ARESR2GPBAR1 | |
| SCHEMBL6848651 | 1.00 | ESR1 (0.33) | ESR1ARESR2GPBAR1 | |
| SCHEMBL10261122 | 1.00 | ESR1 (0.33) | ESR1ARESR2GPBAR1 | |
| SCHEMBL10261589 | 0.76 | — | — | |
| SCHEMBL6847773 | 0.76 | — | — | |
| SCHEMBL12020170 | 0.75 | ESR1 (0.35) | ESR1ARESR2GPBAR1 | |
| SCHEMBL15809885 | 0.75 | ESR1 (0.35) | ESR1ARESR2GPBAR1 | |
| SCHEMBL6847786 | 0.73 | — | — | |
| SCHEMBL10260783 | 0.73 | — | — | |
| SCHEMBL20280526 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172348-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| EP-2457923-A1 | STEROL DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172348-A1 | STEROL DERIVATIVE | NR1H3, NR1H2, SREBF1 | ESR1 491/4885AR 141/4885ESR2 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.