⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8641411 | 0.97 | — | — | |
| SCHEMBL9290792 | 0.84 | — | — | |
| SCHEMBL7852752 | 0.82 | — | — | |
| SCHEMBL4574081 | 0.82 | SPHK2 (0.44) | — | |
| SCHEMBL11406977 | 0.82 | — | — | |
| SCHEMBL9290902 | 0.80 | SPHK2 (0.48) | — | |
| Iodide SCHEMBL5325538 | 0.80 | SPHK2 (0.43) | — | |
| SCHEMBL3093556 | 0.80 | SPHK2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL4575154 | 0.80 | SPHK2 (0.43) | — | |
| SCHEMBL27591516 | 0.80 | SPHK2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264627-A1 | CYCLIC PEPTIDE BINDER AGAINST ONCOGENIC K-RAS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-09-15 | — | — | US | disclosed |
| EP-2364153-B1 | CHITOSAN DERIVATIVES TO OPTIMIZE ANIMAL WEIGHT GAIN | SYNEDGEN INC (US) | 2015-05-06 | — | — | EP | disclosed |
| US-5356895-A | Aminoguanidine derivatives; preventing food spoilage, animal aging | THE ROCKEFELLER UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5140048-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-18 | — | — | US | disclosed |
| US-5128122-A | Nitrogen compound | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5096703-A | Administering aminoguanidine or its salts; oral rinse, tooth paste | THE ROCKEFELLER UNIVERSITY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4983604-A | Aminoguanidine derivatives | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4978684-A | ADMINISTERING AMINOGUANIDINE DERIVATIVE | THE ROCKEFELLER UNIVERSITY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4908446-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0327919-A2 | Method and agents for preventing staining of teeth | THE ROCKEFELLER UNIVERSITY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0316852-A2 | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1989-05-24 | — | — | EP | disclosed |