Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291906 | 1.00 | MAOB (0.56) | MAOBCALM1SLC18A2TAAR1SIGMAR1 | |
| SCHEMBL16838790 | 0.91 | MAOB (0.63) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL14329771 | 0.85 | MAOB (0.57) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL11061464 | 0.85 | MAOB (0.57) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL13038168 | 0.85 | MAOB (0.57) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL11061470 | 0.85 | MAOB (0.57) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL19681498 | 0.84 | MAOB (0.60) | MAOBSLC18A2 | |
| SCHEMBL10479468 | 0.83 | MAOB (0.56) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL10479465 | 0.83 | MAOB (0.56) | MAOBTAAR1SIGMAR1 | |
| SCHEMBL22023702 | 0.83 | HRH3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |
| EP-0343487-A1 | Cyclohexyl esters of alpha-fluoro/carboxylic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1989-11-29 | — | — | EP | disclosed |