Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.68 |
| ▸ | KDM6B | O15054 | 1/20 | 0.59 |
| ▸ | KDM6A | O15550 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181641 | 0.89 | TOP2A (0.59) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL56592 | 0.86 | TOP2A (0.82) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL29401377 | 0.86 | TOP2A (0.82) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL1549736 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL1549406 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL17385621 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL1550654 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL8035666 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL8035668 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 | |
| SCHEMBL1550650 | 0.85 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |