Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836989 | 0.85 | KDM4E (0.35) | MAOBKDM4ECYP1A2GLACYP2C9 | |
| SCHEMBL6832714 | 0.85 | ALDH2 (0.51) | ALDH2ALDH3A1MAOB | |
| SCHEMBL6832877 | 0.79 | ALDH2 (0.51) | ALDH2ALDH3A1MAOB | |
| SCHEMBL6836372 | 0.73 | KDM4E (0.35) | MAOBKDM4ECYP1A2GLACYP2C9 | |
| SCHEMBL9293486 | 0.71 | KDM4E (0.39) | ALDH2ALDH3A1MAOBKDM4ECYP1A2 | |
| SCHEMBL6835949 | 0.71 | TSHR (0.40) | ALDH2ALDH3A1MAOBKDM4ECYP1A2 | |
| SCHEMBL6836680 | 0.71 | ALDH2 (0.58) | ALDH2ALDH3A1MAOBKDM4ECYP1A2 | |
| SCHEMBL6836880 | 0.68 | KDM4E (0.46) | ALDH2ALDH3A1MAOBKDM4ECYP1A2 | |
| SCHEMBL6838797 | 0.68 | KDM4E (0.46) | ALDH2ALDH3A1KDM4ECYP1A2GLA | |
| SCHEMBL6835901 | 0.68 | KDM4E (0.35) | ALDH2ALDH3A1MAOBKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300662-A | Process for producing coumarin and derivatives thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-05 | — | — | US | disclosed |