SCHEMBL929449

SCHEMBL929449

C=CCOc1ccccc1S(=O)(=O)O.[CaH2]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.49
HPGD P15428 2/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SLC22A1 O15245 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
HTR1A P08908 1/20 0.40
CYP2D6 P10635 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378178 0.98 LIG1 (0.50) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL27079 0.98 LIG1 (0.50) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL31591235 0.97 LIG1 (0.49) LIG1HPGDTSHRMAPK1HSD17B10
Ammonia Solution, Strong SCHEMBL14797779 0.97 LIG1 (0.49) LIG1HPGDTSHRMAPK1HSD17B10
Ethylene SCHEMBL1566536 0.97 LIG1 (0.49) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL28664816 0.94 LIG1 (0.47) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL8615075 0.91 LIG1 (0.44) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL1702122 0.85 LIG1 (0.44) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL7764681 0.83 CA1 (0.53) LIG1HPGDTSHRMAPK1HSD17B10
SCHEMBL30269714 0.83 CA1 (0.53) LIG1HPGDTSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1016706-A2 Lubricating oil composition for internal combustion engines having improved thermal oxidation durability and detergency ORONITE JAPAN LIMITED (JP) 2000-07-05 EP claimed
EP-1803794-B1 Diesel engine lubricating oil composition for large-bore two-stroke cross-head diesel engines CHEVRONTEXACO JAPAN LTD (JP) 2014-06-25 EP disclosed
US-7956021-B2 Diesel engine lubricating oil composition for large-bore two-stroke cross-head diesel engines CHEVRON JAPAN LTD. (US) 2011-06-07 US disclosed
US-7875577-B2 overbased sulfurized alkylphenol calcium salt detergent, overbased calcium alkylbenzenesulfonate detergent, nitrogen-containing ashless dispersant, and zinc dihydrocarbyldithiophosphate CHEVRON JAPAN LTD. (US) 2011-01-25 US disclosed
EP-1803794-A1 Diesel engine lubricating oil composition for large-bore two-stroke cross-head diesel engines ChevronTexaco Japan Ltd (JP) 2007-07-04 EP disclosed
US-20070149421-A1 DIESEL ENGINE LUBRICATING OIL COMPOSITION FOR LARGE-BORE TWO-STROKE CROSS-HEAD DIESEL ENGINES CHEVRON JAPAN LTD. 2007-06-28 US disclosed
US-20070149420-A1 DIESEL ENGINE LUBRICATING OIL COMPOSITION FOR LARGE-BORE TWO-STROKE CROSS-HEAD DIESEL ENGINES CHEVRON JAPAN LTD. 2007-06-28 US disclosed
EP-1016706-A2 Lubricating oil composition for internal combustion engines having improved thermal oxidation durability and detergency ORONITE JAPAN LIMITED (JP) 2000-07-05 EP disclosed