Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190830 | 0.90 | MAPT (0.68) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL28159221 | 0.88 | MAPT (0.66) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9296572 | 0.88 | KDM4E (0.57) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL29478093 | 0.87 | MAPT (0.61) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL28385011 | 0.87 | MAPT (0.61) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL4712947 | 0.87 | KDM4E (0.56) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL21682173 | 0.84 | KDM4E (0.54) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL505728 | 0.80 | KDM4E (0.69) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL29466280 | 0.79 | KDM4E (0.68) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL3729071 | 0.79 | KDM4E (0.68) | KDM4ESMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344896-A | Alkylsulfonate-containing polymers from tetraaminobenzene and benzothiazole-substituted terephthalic acids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1994-09-06 | — | — | US | disclosed |
| US-5312876-A | Copolybenzobisthiazoles and benzobisoxazoles with benzimidazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1994-05-17 | — | — | US | disclosed |