Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 12/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 9/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187942 | 1.00 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL9299199 | 1.00 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL642481 | 0.86 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7890460 | 0.86 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL7455717 | 0.86 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9298944 | 0.86 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL642482 | 0.86 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9298943 | 0.86 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL12589787 | 0.85 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL9299052 | 0.85 | GRIK1 (0.52) | GRIK1GRIA2CYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618810-A4 | BRADYKININ ANTAGONIST PEPTIDES. | SCIOS NOVA INC (US) | 1994-12-07 | — | — | EP | disclosed |
| EP-0618810-A1 | BRADYKININ ANTAGONIST PEPTIDES | SCIOS NOVA INC. (US) | 1994-10-12 | — | — | EP | disclosed |