Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136791 | 0.86 | CYP3A4 (0.41) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL545529 | 0.78 | DRD1 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL28507862 | 0.76 | CYP3A4 (0.41) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL8136787 | 0.76 | TSHR (0.41) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL9299380 | 0.75 | CYP3A4 (0.38) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11528911 | 0.75 | CYP3A4 (0.44) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL28943070 | 0.73 | SLC6A4 (0.41) | CYP3A4TSHRMAPK1DRD1CYP1A2 | |
| SCHEMBL28331501 | 0.73 | TDP1 (0.39) | CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL9578597 | 0.73 | ESR2 (0.44) | — | |
| SCHEMBL180952 | 0.73 | TSHR (0.45) | CYP3A4TSHRMAPK1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288756-A | Pesticides, miticides, larvicides; nontoxic to warm blood animals | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| US-5153224-A | Insecticide or pesticide | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-5107017-A | Insecticides | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-4980506-A | Benzoylphenylureas | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| US-4798837-A | Benzoylphenylureas | CIBA-GEIGY CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |