Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.73 |
| ▸ | PRTN3 | P24158 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483720 | 0.85 | ELANE (1.00) | ELANEPRTN3 | |
| SCHEMBL22369614 | 0.84 | ELANE (0.86) | ELANEPRTN3 | |
| SCHEMBL3657617 | 0.83 | ELANE (0.76) | ELANEPRTN3THRB | |
| SCHEMBL16189796 | 0.83 | ELANE (0.76) | ELANEPRTN3 | |
| SCHEMBL3657615 | 0.83 | ELANE (0.76) | ELANEPRTN3 | |
| SCHEMBL9670071 | 0.82 | ELANE (0.70) | ELANEPRTN3 | |
| SCHEMBL7276499 | 0.81 | ELANE (0.73) | ELANEPRTN3 | |
| SCHEMBL14870980 | 0.81 | ELANE (0.73) | ELANEPRTN3 | |
| SCHEMBL10973406 | 0.81 | ELANE (0.73) | ELANEPRTN3 | |
| SCHEMBL23896984 | 0.80 | ELANE (0.71) | ELANEPRTN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356894-A | Adenosine antagonists | SYNGENTA LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| US-5326869-A | Chemical process | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1994-07-05 | — | — | US | disclosed |
| US-5270311-A | [1,2,4]-Triazolo[1,5-a]and pyrazolo[2,3-a][1,3,5]triazine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0544444-A1 | Processes for the preparation f substituted triazolo 1,5-a 1,3,5 triazines | ZENECA LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0459702-A1 | Azole Derivatives | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |