Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 9/20 | 0.59 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR1A | P08908 | 7/20 | 0.57 |
| ▸ | HTR2C | P28335 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300393 | 0.96 | HTR1D (0.66) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9298882 | 0.90 | HTR1D (0.77) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300695 | 0.89 | HTR1D (0.66) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9298881 | 0.87 | HTR1D (0.80) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL5318083 | 0.83 | HTR1D (0.80) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300151 | 0.83 | HTR1D (0.59) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9296216 | 0.82 | HTR1D (0.68) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300547 | 0.81 | HTR1D (0.75) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300281 | 0.81 | HTR1D (0.71) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300061 | 0.80 | HTR1D (0.73) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | claimed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | claimed |
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |