Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 0.79 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.77 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.77 |
| ▸ | HTR1B | P28222 | 5/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.69 |
| ▸ | HTR1A | P08908 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | HTR2C | P28335 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.69 |
| ▸ | HTR3B | O95264 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300606 | 0.90 | HTR1D (0.86) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9299335 | 0.90 | HTR1D (0.79) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9299339 | 0.90 | HTR1D (0.79) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9091365 | 0.89 | HTR1D (0.84) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300006 | 0.89 | HTR1D (0.81) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL29611473 | 0.88 | HTR1D (0.77) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL7724517 | 0.88 | HTR1D (0.77) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL7883949 | 0.88 | HTR1D (0.79) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL7883917 | 0.88 | HTR1D (0.82) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A | |
| SCHEMBL9300777 | 0.88 | HTR1D (0.79) | HTR1DSLC6A4TMPRSS2HTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356893-A | Antidepressants, nervous system disorders | GLAXO GROUP LIMITED (GB) | 1994-10-18 | — | — | US | disclosed |
| EP-0533266-A1 | Benzanilide derivatives as 5-HT1D antagonists | GLAXO GROUP LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |