Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512475 | 0.79 | PDE10A (0.77) | CYSLTR1GPBAR1CYSLTR2PDE10ACYP1A2 | |
| SCHEMBL6088376 | 0.77 | CYSLTR1 (0.72) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL10547998 | 0.76 | CYSLTR1 (1.00) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL6744402 | 0.76 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2PDE10ATP53 | |
| SCHEMBL10545363 | 0.76 | CYSLTR1 (0.71) | CYSLTR1GPBAR1CYSLTR2PDE10ATP53 | |
| SCHEMBL9047808 | 0.76 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2PDE10ACYP1A2 | |
| SCHEMBL10690028 | 0.76 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2PDE10ATP53 | |
| Hydrogen Sulfide SCHEMBL9818428 | 0.76 | CYSLTR1 (0.71) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL10510977 | 0.76 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2PDE10ATP53 | |
| SCHEMBL10513942 | 0.76 | CYSLTR1 (0.69) | CYSLTR1GPBAR1CYSLTR2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360909-A | THROMBOXANE A2 ANTAGONIST | TERUMO KABUSHIKI KAISHA (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0562796-A1 | Phenoxyacetic acid compounds and medical preparations containing them | TERUMO KABUSHIKI KAISHA (JP) | 1993-09-29 | — | — | EP | disclosed |