SCHEMBL9301514

SCHEMBL9301514

CCCCN(CCCC)CCCC.CCCCNCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP2C19 P33261 2/20 0.41
MEN1 O00255 1/20 0.41
GLA P06280 1/20 0.41
KMT2A Q03164 1/20 0.41
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH7 P40394 1/20 0.40
PAOX Q6QHF9 1/20 0.39
CYP1A2 P05177 1/20 0.39
KDM5A P29375 3/20 0.38
PHF8 Q9UPP1 2/20 0.36
KDM4C Q9H3R0 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
S1PR2 O95136 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356135 0.97 TSHR (0.52) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL11749668 0.97 TSHR (0.52) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL8345906 0.95 TSHR (0.50) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL8009387 0.95 TSHR (0.50) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL1087132 0.94 TSHR (0.55) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL10896661 0.93 TSHR (0.55) TSHRALDH1A1CYP2C19ADH1BADH1C
SCHEMBL9814187 0.93 TSHR (0.55) TSHRALDH1A1CYP2C19ADH1BADH1C
SCHEMBL6142226 0.93 TSHR (0.48) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL8000190 0.93 TSHR (0.67) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL18244864 0.89 TSHR (0.55) TSHRALDH1A1CYP2C19MEN1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0613450-A1 PROCESS OF GROWING CRYSTALLINE MICROPOROUS SOLIDS IN A FLUORIDE-CONTAINING, SUBSTANTIALLY NON-AQUEOUS GROWTH MEDIUM. DOW CHEMICAL CO (US) 1994-09-07 EP disclosed
WO-1993010044-A1 PROCESS OF GROWING CRYSTALLINE MICROPOROUS SOLIDS IN A FLUORIDE-CONTAINING, SUBSTANTIALLY NON-AQUEOUS GROWTH MEDIUM THE DOW CHEMICAL COMPANY (US) 1993-05-27 WO disclosed