Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172974 | 0.91 | TSHR (0.42) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL4582548 | 0.80 | MEN1 (0.43) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL23945291 | 0.80 | TSHR (0.44) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL19850554 | 0.80 | TSHR (0.44) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL21938814 | 0.80 | TSHR (0.44) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL28057060 | 0.80 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL21939213 | 0.77 | TSHR (0.41) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL7677772 | 0.74 | TSHR (0.42) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22043185 | 0.74 | EPHX2 (0.40) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20968115 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373061-A | Polyolefins having active groups on its backbone | ARISTECH CHEMICAL CORPORATION (US) | 1994-12-13 | — | — | US | disclosed |
| US-5367090-A | Unsaturated silane monomers | ARISTECH CHEMICAL CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| US-5329037-A | Olefin monomers containing a protective alkyl silane group | ARISTECH CHEMICAL CORPORATION (US) | 1994-07-12 | — | — | US | disclosed |
| US-5296626-A | Monomers for polymers containing silanol groups with unsaturated groups | ARISTECH CHEMICAL CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| US-5296562-A | Ziegler-Natta catalytic addition polymerization of olefin and unsaturated silanol derivatives | ARISTECH CHEMICAL CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| US-5294679-A | Polymerization of an alpha olefin and an unsaturated silyl compound using a coordination catalyst of titanium chloride on a magnesium chloride support followed by hydroysis or alcoholyzing | ARISTECH CHEMICAL CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0316369-B1 | INCORPORATION OF FUNCTIONAL GROUPS IN POLYMERS | Aristech Chemical Corporation (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0363990-A2 | Incorporation of functional groups in polymers | Aristech Chemical Corporation (US) | 1990-04-18 | — | — | EP | disclosed |
| EP-0316369-A1 | INCORPORATION OF FUNCTIONAL GROUPS IN POLYMERS. | ARISTECH CHEMICAL CORP (US) | 1989-05-24 | — | — | EP | disclosed |
| WO-1988008856-A1 | INCORPORATION OF FUNCTIONAL GROUPS IN POLYMERS | ARISTECH CHEMICAL CORPORATION (US) | 1988-11-17 | — | — | WO | disclosed |