Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357608 | 1.00 | PDE4A (0.52) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL29029329 | 0.81 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL21274469 | 0.79 | PDE4A (0.41) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL8020544 | 0.79 | PDE4A (0.41) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Mannitol SCHEMBL27777220 | 0.79 | PDE4A (0.50) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL27029518 | 0.78 | PDE4A (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL524751 | 0.75 | OR51E2 (0.42) | — | |
| Adonitol SCHEMBL28119564 | 0.75 | PDE4A (0.45) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1513883 | 0.74 | PDE4A (0.45) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Mannitol SCHEMBL19410667 | 0.74 | PDE4A (0.58) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861413-B1 | AZETIDINIUM-CONTAINING COPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2019-05-01 | — | — | EP | claimed |
| JP-57026746-A | — | — | None | — | — | JP | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| JP-S5726746-A | DETERMINING METHOD OF HEMOGLOBIN BOUND TO GLUCOSE | SEKISUI CHEM CO LTD | 1982-02-12 | — | — | JP | disclosed |