Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830186 | 1.00 | CHRM1 (0.64) | CHRM1KDM4ELMNAHPGDHTT | |
| Hydrochloric Acid SCHEMBL28880680 | 0.89 | P4HTM (0.58) | CHRM1KDM4ELMNAHPGDHTT | |
| SCHEMBL19031875 | 0.88 | KDM4E (0.51) | CHRM1KDM4ELMNAHPGDHTT | |
| SCHEMBL27628032 | 0.86 | CHRM1 (0.60) | CHRM1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL6310886 | 0.85 | CHRM1 (0.58) | CHRM1KDM4ELMNAHPGDHTT | |
| SCHEMBL599399 | 0.82 | EPHX1 (0.71) | CHRM1P4HTMEPHX1CPA1CYP1A2 | |
| SCHEMBL3079795 | 0.82 | EPHX1 (0.71) | CHRM1P4HTMEPHX1CPA1CYP1A2 | |
| SCHEMBL67234 | 0.82 | EPHX1 (0.71) | CHRM1P4HTMEPHX1CPA1CYP1A2 | |
| SCHEMBL7816162 | 0.81 | CHRM1 (0.61) | CHRM1LMNAHTTSMN1; SMN2P4HTM | |
| SCHEMBL7816160 | 0.81 | CHRM1 (0.61) | CHRM1LMNAHTTSMN1; SMN2P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292749-A | Quinuclidine derivatives; bronchodilator agents, treatment of respiratory system disorders | PFIZER INC. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0500864-A1 | ANTIMUSCARINIC BRONCHODILATORS | Pfizer Limited (GB) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004346-A1 | ANTIMUSCARINIC BRONCHODILATORS | PFIZER LIMITED (GB) | 1992-03-19 | — | — | WO | disclosed |