Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.68 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827475 | 0.88 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10607508 | 0.84 | CYSLTR1 (0.71) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL9828564 | 0.84 | CYSLTR1 (0.65) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10607417 | 0.83 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10544473 | 0.82 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10549147 | 0.82 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL3076102 | 0.81 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8317460 | 0.81 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8001866 | 0.81 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL27814925 | 0.81 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5246994-A | — | — | None | — | — | JP | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-RE40558-E1 | Therapeutic uses of di-aryl acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-5310744-A | Antiinflammatory | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5288733-A | Quinolylmethoxyphenylacetic acid acylamides and ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| JP-H05246994-A | QUINOLYLMETHOXYPHENYL-ACETAAMIDES | BAYER AG | 1993-09-24 | — | — | JP | disclosed |
| EP-0545170-A1 | Quinolylmethoxyphenylacetamides | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0545171-A1 | Quinolylmethoxyphenyl acetic acid acylamides and ureas | BAYER AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |