Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303054 | 0.83 | P2RY14 (0.55) | TTRP2RY14 | |
| SCHEMBL7554285 | 0.69 | MEN1 (0.55) | TTRP2RY14KDM4E | |
| SCHEMBL30363668 | 0.69 | MEN1 (0.55) | TTRP2RY14KDM4E | |
| SCHEMBL8089430 | 0.69 | PTPN1 (0.53) | TTRPTPRC | |
| SCHEMBL10577207 | 0.69 | TTR (0.44) | TTRMAP4K4ALPLPTPRCKDM4E | |
| SCHEMBL7907125 | 0.68 | RARB (0.54) | CA12CA9KDM4E | |
| SCHEMBL28410867 | 0.67 | MEN1 (0.52) | AKR1C3AKR1C2KDM4E | |
| SCHEMBL3927793 | 0.67 | TSHR (0.59) | TTRMAP4K4ALPLPTPRCKDM4E | |
| SCHEMBL15124553 | 0.67 | CYP2A6 (0.54) | TTRMAP4K4ALPLKDM4ENPC1 | |
| SCHEMBL5924860 | 0.67 | CYP2A6 (0.54) | TTRMAP4K4ALPLKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281720-A | Antiasthmatics, antiallergens, antiinflammatory agents and cytoprotective agents | MERCK FROSST CANADA, INC. | 1994-01-25 | — | — | US | disclosed |