Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.76 |
| ▸ | F3 | P13726 | 2/20 | 0.76 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.68 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | MGAM | O43451 | 3/20 | 0.67 |
| ▸ | SI | P14410 | 3/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524260 | 1.00 | CYP2C9 (0.76) | CYP2C9HSD11B1F3AKR1C3AKR1C1 | |
| SCHEMBL1524262 | 1.00 | CYP2C9 (0.76) | CYP2C9HSD11B1F3AKR1C3AKR1C1 | |
| SCHEMBL624726 | 0.96 | CYP2C9 (0.70) | CYP2C9HSD11B1F3AKR1C3AKR1C1 | |
| SCHEMBL14473217 | 0.86 | CYP2C9 (1.00) | CYP2C9HSD11B1F3GAAHTT | |
| SCHEMBL5585181 | 0.86 | CYP2C9 (1.00) | CYP2C9HSD11B1F3GAAHTT | |
| SCHEMBL5585182 | 0.86 | CYP2C9 (1.00) | CYP2C9HSD11B1F3GAAHTT | |
| SCHEMBL2025881 | 0.82 | CYP2C9 (0.61) | CYP2C9HSD11B1F3AKR1C3AKR1C1 | |
| SCHEMBL11218557 | 0.82 | AKR1C3 (0.70) | CYP2C9HSD11B1F3AKR1C3AKR1C1 | |
| SCHEMBL11218559 | 0.82 | AKR1C3 (0.70) | CYP2C9HSD11B1F3AKR1C3AKR1C1 | |
| SCHEMBL17077402 | 0.81 | EGFR (0.57) | CYP2C9HSD11B1F3AKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281622-A | Administering to mammals as antiinflammatory agent | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5250735-A | Antitumor or antiinflammatory agents, analgesics | UNIVERSITY OF PITTSBURGH (US) | 1993-10-05 | — | — | US | disclosed |