Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 5/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718931 | 0.95 | ATM (0.44) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL395579 | 0.93 | ATM (0.43) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL9764023 | 0.89 | ATM (0.40) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL9304052 | 0.87 | ATM (0.43) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL21802985 | 0.87 | ATM (0.43) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL9301205 | 0.87 | ATM (0.43) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL8627525 | 0.86 | ATM (0.53) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL9063614 | 0.86 | ATM (0.53) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL21802955 | 0.85 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL22367597 | 0.85 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427666-B2 | Silicone-containing acrylic polymers for transdermal drug delivery compositions | NOVEN PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200277424-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3179989-B1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMA (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-3179989-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | Noven Pharmaceuticals, INC. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016018858-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | WO | disclosed |
| US-20160030362-A1 | SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS | NOVEN PHARMACEUTICALS, INC. (US) | 2016-02-04 | — | — | US | disclosed |
| US-5376378-A | Transdermal drug delivery | CIBA-GEIGY CORP. (US) | 1994-12-27 | — | — | US | disclosed |
| US-5288827-A | Drug selivery | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |