Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 8/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929062 | 0.84 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL929540 | 0.84 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL7718893 | 0.84 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL24359897 | 0.82 | ACE (0.51) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL929932 | 0.81 | KDM4E (0.40) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL929929 | 0.81 | KDM4E (0.40) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL929930 | 0.81 | KDM4E (0.40) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL11339071 | 0.79 | FOLH1 (0.37) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL10947858 | 0.79 | FOLH1 (0.37) | FOLH1ACEGRNSORT1MME | |
| SCHEMBL4954782 | 0.77 | FOLH1 (0.36) | FOLH1ACEMMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292926-A | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0326326-B1 | CYSTEINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| EP-0326326-A1 | Cysteine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |