Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.63 |
| ▸ | AANAT | Q16613 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677886 | 0.88 | MEN1 (0.84) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL7849865 | 0.84 | MEN1 (0.74) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL7677332 | 0.84 | GFER (0.74) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL9302879 | 0.82 | MEN1 (0.71) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL9303476 | 0.82 | MEN1 (0.71) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL9303912 | 0.82 | MEN1 (0.71) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL7851164 | 0.82 | MEN1 (0.71) | MEN1KMT2AGFERMTNR1AAANAT | |
| SCHEMBL20797914 | 0.81 | MC5R (0.68) | MEN1KMT2AMAPTSMN1; SMN2CDK2 | |
| SCHEMBL32667932 | 0.81 | MC5R (0.68) | MEN1KMT2AMAPTSMN1; SMN2CDK2 | |
| SCHEMBL9117842 | 0.81 | MEN1 (0.76) | MEN1KMT2AGFERMTNR1AAANAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283343-A | Melatonin antagonists | WHITBY RESEARCH, INC. (US) | 1994-02-01 | — | — | US | disclosed |
| US-5093352-A | Melatonin inhibitor, sleep, 2-aryl N-acetyl tryptamine | WHITBY RESEARCH, INC. (US) | 1992-03-03 | — | — | US | disclosed |