Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844102 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL12188930 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL20946378 | 0.84 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL12189228 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL13846055 | 0.81 | MAPK1 (1.00) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL10082160 | 0.81 | MAPK1 (1.00) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL12719599 | 0.81 | MAPK1 (1.00) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL2834532 | 0.81 | MAPK1 (1.00) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL12315297 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4ERECQLMAPK1HTT | |
| SCHEMBL21292902 | 0.79 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4ERECQLMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |