Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614177 | 0.93 | TSHR (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL611564 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL614616 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL18099453 | 0.84 | TSHR (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11767225 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28765737 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL5268214 | 0.83 | TSHR (0.54) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL3841766 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL8925522 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL14840164 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362775-A | Seals for semiconductors or moldings | NIPPONDENSO CO., LTD. (JP) | 1994-11-08 | — | — | US | claimed |