SCHEMBL9302927

SCHEMBL9302927

O=C(O)CCCCCCCCCCCCCCCCCCCCC/C=C\CCCCCCO

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.73
FFAR4 Q5NUL3 2/20 0.73
GPR84 Q9NQS5 1/20 0.73
PPARG P37231 4/20 0.67
PPARD Q03181 4/20 0.67
PPARA Q07869 4/20 0.67
MAPT P10636 4/20 0.67
F7 P08709 4/20 0.67
F3 P13726 4/20 0.67
TERT O14746 3/20 0.67
PTPN1 P18031 3/20 0.67
BLM P54132 3/20 0.67
HSD17B10 Q99714 3/20 0.67
FABP4 P15090 2/20 0.67
LMNA P02545 2/20 0.67
ALOX15 P16050 2/20 0.67
RECQL P46063 2/20 0.67
DUSP3 P51452 2/20 0.67
CYP19A1 P11511 2/20 0.67
PTGS1 P23219 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15515107 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL19857556 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL9301707 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL1273763 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL23950035 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL23225824 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL23925417 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL23925418 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL22634134 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD
SCHEMBL1950745 1.00 FFAR1 (0.73) FFAR1FFAR4GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0097059-A2 Skin treatment compositions UNILEVER N.V. (NL) 1983-12-28 EP claimed
US-5342976-A Long chain omega-hydroxy fatty acid or a carboxy-substituted derivative; imparts barrier function to prevent moisture loss ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1994-08-30 US disclosed
US-5202357-A Skin barrier LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-04-13 US disclosed
US-4950688-A CONTROLLING SKIN BARRIER FUNCTION; HYDROXY FATTY ACID OR ESTER CONOPCO, INC. (US) 1990-08-21 US disclosed