Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303078 | 1.00 | F2 (0.52) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL8203714 | 1.00 | F2 (0.52) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11412150 | 0.96 | F2 (0.51) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL8045353 | 0.96 | F2 (0.55) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL8029232 | 0.96 | F2 (0.55) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11412686 | 0.95 | F2 (0.50) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11409445 | 0.95 | F2 (0.50) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11407526 | 0.95 | F2 (0.50) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11405609 | 0.95 | F2 (0.52) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9302511 | 0.94 | F2 (0.51) | F2THRBKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-5286410-A | Positive dielectric anisotropy | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5211878-A | Difluorobenzonitrile derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5178790-A | With excellent steepness of characteristics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-01-12 | — | — | US | disclosed |