Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302976 | 0.97 | CNR1 (0.54) | MAPTCNR1CNR2DRD1HRH2 | |
| SCHEMBL9301629 | 0.92 | CNR1 (0.59) | CNR1CNR2 | |
| SCHEMBL9301137 | 0.87 | CNR2 (0.52) | CNR1CNR2 | |
| SCHEMBL9303207 | 0.81 | CNR1 (0.63) | CNR1DRD1HRH2HTR2AHTR2C | |
| SCHEMBL2049777 | 0.81 | MEN1 (0.60) | CNR1CNR2 | |
| SCHEMBL10650580 | 0.80 | MAPT (0.57) | MAPTCNR1CNR2 | |
| SCHEMBL2033984 | 0.79 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL2076737 | 0.79 | CNR2 (0.78) | CNR1CNR2 | |
| SCHEMBL27034080 | 0.78 | CNR2 (0.69) | CNR1CNR2 | |
| SCHEMBL15478842 | 0.77 | CNR2 (0.75) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324737-A | Analgesics, antirheumatic and antiinflammatory agents, glaucoma | STERLING WINTHROP INC. (US) | 1994-06-28 | — | — | US | claimed |