SCHEMBL9303527

SCHEMBL9303527

C=C(C)C(=O)OCCCCC(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
THRB P10828 1/20 0.47
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 4/20 0.37
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.30
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024908 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4236447 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10678713 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9301950 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17078642 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4773867 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1419276 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6849323 0.94 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28866183 0.87 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL14330801 0.87 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9494860-B2 Resist composition, method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2016-11-15 US disclosed
US-20120164578-A1 RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2012-06-28 US disclosed
US-7838190-B2 Electrophotographic photosensitive member with surface layer of fluororesin particles and polyolefin with perfluoroalkyl group CANON KABUSHIKI KAISHA (JP) 2010-11-23 US disclosed
US-20090130576-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-05-21 US disclosed
US-5336582-A Electrophotographic image formation comprising an arylamine in a charge transport layer and an encapsulated toner FUJI XEROX CO., LTD. (JP) 1994-08-09 US disclosed
US-5300388-A Toner for electrophotography and process for producing the same FUJI XEROX CO., LTD. (JP) 1994-04-05 US disclosed