Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303987 | 0.88 | ALOX5AP (0.79) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9303871 | 0.86 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9305011 | 0.85 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9305053 | 0.84 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL30181605 | 0.84 | ALOX5AP (0.79) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9146239 | 0.84 | ALOX5AP (0.79) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9316128 | 0.84 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9305688 | 0.83 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9303684 | 0.83 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9305251 | 0.83 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288743-A | Lipoxygenase inhibitors | ABBOTT LABORATORIES (US) | 1994-02-22 | — | — | US | disclosed |