Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 2/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302826 | 0.91 | PTAFR (0.83) | PTAFRHRH3HDAC1HDAC6GALR3 | |
| SCHEMBL9301610 | 0.88 | PTAFR (1.00) | PTAFRHRH3HDAC1HDAC6GALR3 | |
| SCHEMBL4937590 | 0.79 | PTAFR (0.79) | PTAFRHRH3HDAC1HDAC6 | |
| SCHEMBL4945297 | 0.79 | HRH3 (0.90) | PTAFRHRH3 | |
| SCHEMBL3724608 | 0.79 | HRH3 (0.90) | PTAFRHRH3 | |
| SCHEMBL4937585 | 0.79 | PTAFR (0.79) | PTAFRHRH3HDAC1HDAC6 | |
| SCHEMBL3668224 | 0.79 | HRH3 (0.92) | PTAFRHRH3 | |
| SCHEMBL3724043 | 0.79 | HRH3 (0.98) | PTAFRHRH3 | |
| SCHEMBL9302862 | 0.78 | PTAFR (0.78) | PTAFRHRH3HDAC1HDAC6RAB9A | |
| SCHEMBL3726475 | 0.78 | PTAFR (0.81) | PTAFRHRH3HDAC1HDAC6GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |