SCHEMBL9303923

SCHEMBL9303923

C=CC(=O)OC(C)C(C)[Si](O[SiH2]C)(O[SiH2]C)O[SiH2]C

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9303494 0.77 TSHR (0.40) TSHR
SCHEMBL26841662 0.74 TSHR (0.50) TSHR
SCHEMBL1284885 0.71 TSHR (0.46) TSHR
SCHEMBL8965914 0.71 TSHR (0.46) TSHR
SCHEMBL9302018 0.70 TSHR (0.36) TSHR
SCHEMBL9302665 0.70 TSHR (0.36) TSHR
Hydrochloric Acid SCHEMBL15641108 0.69 TSHR (0.45) TSHR
SCHEMBL1374266 0.69 TSHR (0.45) TSHR
SCHEMBL8966172 0.69 TSHR (0.45) TSHR
SCHEMBL10758374 0.69 TSHR (0.45) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5288827-A Drug selivery CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed