Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.53 |
| ▸ | OGA | O60502 | 2/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303366 | 1.00 | KMT2A (0.60) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9302681 | 0.87 | HRH3 (0.56) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9305371 | 0.85 | HRH3 (0.49) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9301934 | 0.85 | HRH3 (0.49) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9303977 | 0.83 | HRH3 (0.48) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9304217 | 0.83 | HRH3 (0.48) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9303243 | 0.82 | KMT2A (0.49) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9303849 | 0.82 | KMT2A (0.49) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9305171 | 0.81 | KMT2A (0.48) | KMT2ANPC1RAB9AHRH3OGA | |
| SCHEMBL9205767 | 0.80 | HRH3 (0.58) | KMT2ANPC1RAB9AHRH3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356559-A | Optically active piperazinyl derivatives as liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |