Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559391 | 0.89 | KMT2A (0.44) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL587574 | 0.88 | KMT2A (0.44) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL7559624 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL18468249 | 0.87 | MEN1 (0.52) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL8526820 | 0.87 | KMT2A (0.44) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL28126645 | 0.86 | TSHR (0.55) | MAPTMEN1KMT2ATSHRCA12 | |
| SCHEMBL8529751 | 0.85 | HSD17B10 (0.50) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL18468247 | 0.83 | TSHR (0.55) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL20505300 | 0.83 | TSHR (0.47) | MAPTMEN1KMT2ANPSR1TSHR | |
| SCHEMBL6160953 | 0.81 | TSHR (0.53) | MAPTMEN1KMT2ANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5329041-A | For herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-07-12 | — | — | US | disclosed |
| WO-1992012957-A1 | TRISUBSTITUTED BENZOIC ACID INTERMEDIATES | NGUYEN NHAN H (US) | 1992-08-06 | — | — | WO | disclosed |