SCHEMBL9304327

SCHEMBL9304327

CC(C)=CCCC(C)=CCCC(C)=CCOCC(C(=O)O)P(=O)(O)O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 15/20 0.57
PGGT1B P53609 6/20 0.57
FNTB P49356 10/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9304322 1.00 FNTA (0.57) FNTAPGGT1BFNTB
SCHEMBL9304800 0.87 FNTA (0.55) FNTAPGGT1BFNTB
SCHEMBL9304811 0.87 FNTA (0.55) FNTAPGGT1BFNTB
SCHEMBL9305257 0.83 FNTA (0.49) FNTAPGGT1BFNTB
SCHEMBL9305253 0.83 FNTA (0.49) FNTAPGGT1BFNTB
SCHEMBL8462990 0.81 FNTA (0.57) FNTAPGGT1BFNTB
SCHEMBL8460925 0.81 FNTA (0.66) FNTAPGGT1BFNTB
SCHEMBL8462988 0.81 FNTA (0.57) FNTAPGGT1BFNTB
SCHEMBL8461627 0.81 FNTA (0.66) FNTAPGGT1BFNTB
SCHEMBL9304773 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601573-A1 Alpha-phosphonocarboxylate squalene synthetase inhibitors and method BRISTOL-MYERS SQUIBB COMPANY (US) 1994-06-15 EP claimed
EP-0601573-A1 Alpha-phosphonocarboxylate squalene synthetase inhibitors and method BRISTOL-MYERS SQUIBB COMPANY (US) 1994-06-15 EP disclosed
US-5312814-A Antilipemic agents or anticholesterol agents BRISTOL-MYERS SQUIBB CO. (US) 1994-05-17 US disclosed