Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165643 | 0.80 | TDP1 (1.00) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL22151 | 0.80 | TDP1 (1.00) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL16925719 | 0.80 | TDP1 (1.00) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL17517216 | 0.80 | TDP1 (1.00) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL9678882 | 0.77 | TDP1 (0.93) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| Hydrochloric Acid SCHEMBL8841253 | 0.77 | TDP1 (0.93) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL8078228 | 0.77 | TDP1 (0.93) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL269896 | 0.77 | TDP1 (0.93) | TDP1LMNASMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL9355977 | 0.77 | TDP1 (0.93) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 | |
| SCHEMBL1318745 | 0.77 | TDP1 (0.93) | TDP1LMNAMAPTSMN1; SMN2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |