Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494077 | 1.00 | TSHR (0.50) | TSHRCYP3A4KMT2AMEN1THRB | |
| SCHEMBL9304758 | 0.85 | — | — | |
| SCHEMBL166345 | 0.85 | — | — | |
| SCHEMBL10367143 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL29104715 | 0.82 | — | — | |
| SCHEMBL525604 | 0.80 | KMT2A (0.52) | TSHRKMT2ATHRBALDH1A1 | |
| SCHEMBL9954593 | 0.80 | KMT2A (0.52) | TSHRKMT2ATHRBALDH1A1 | |
| SCHEMBL11385081 | 0.80 | KMT2A (0.46) | TSHRCYP3A4KMT2AALDH1A1SMN1; SMN2 | |
| Chloromethane SCHEMBL18979918 | 0.80 | — | — | |
| SCHEMBL9954026 | 0.80 | KMT2A (0.52) | TSHRKMT2ATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328993-A | Dyeing plastics; colorfastness, photostability | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |